Recently, there has been an interest in improving the resources available in Intrusion Detection System (IDS) techniques. In this sense, several studies related to cybersecurity show that the environment invasions and information kidnapping are increasingly recurrent and complex. The criticality of the business involving operations in an environment using computing resources does not allow the vulnerability of the information. Cybersecurity has taken on a dimension within the universe of indispensable technology in corporations, and the prevention of risks of invasions into the environment is dealt with daily by Security teams. Thus, the main objective of the study was to investigate the Ensemble Learning technique using the Stacking method, supported by the Support Vector Machine (SVM) and k-Nearest Neighbour (kNN) algorithms aiming at an optimization of the results for DDoS attack detection. For this, the Intrusion Detection System concept was used with the application of the Data Mining and Machine Learning Orange tool to obtain better results

Identifying anomalies has become one of the primary strategies towards security and protection procedures in computer networks. In this context, machine learning-based methods emerge as an elegant solution to identify such scenarios and learn irrelevant information so that a reduction in the identification time and possible gain in accuracy can be obtained. This paper proposes a novel feature selection approach called Finite Element Machines for Feature Selection (FEMa-FS), which uses the framework of finite elements to identify the most relevant information from a given dataset. Although FEMa-FS can be applied to any application domain, it has been evaluated in the context of anomaly detection in computer networks. The outcomes over two datasets showed promising results.

科学机器学习（SCIML）是对几个不同应用领域的兴趣越来越多的领域。在优化上下文中，基于SCIML的工具使得能够开发更有效的优化方法。但是，必须谨慎评估和执行实施优化的SCIML工具。这项工作提出了稳健性测试的推论，该测试通过表明其结果尊重通用近似值定理，从而确保了基于多物理的基于SCIML的优化的鲁棒性。该测试应用于一种新方法的框架，该方法在一系列基准测试中进行了评估，以说明其一致性。此外，将提出的方法论结果与可行优化的可行区域进行了比较，这需要更高的计算工作。因此，这项工作为保证在多目标优化中应用SCIML工具的稳健性测试提供了比存在的替代方案要低的计算努力。

味道是遵循社会趋势和行为的风味行业的焦点。新调味剂和分子的研究和开发在该领域至关重要。另一方面，自然风味的发展在现代社会中起着至关重要的作用。鉴于此，目前的工作提出了一个基于科学机器学习的新颖框架，以在风味工程和行业中解决新的问题。因此，这项工作带来了一种创新的方法来设计新的自然风味分子。评估了有关合成可及性，原子数以及与天然或伪天然产物的相似性的分子。

数字乳房X光检查仍然是乳腺癌筛选最常见的成像工具。虽然使用数字乳房X线照相术用于癌症筛查的益处超过了与X射线曝光相关的风险，但是辐射剂量必须尽可能低，同时保持所产生的图像的诊断效用，从而最大限度地减少患者风险。许多研究通过使用深神经网络恢复低剂量图像来调查剂量降低的可行性。在这些情况下，选择适当的培训数据库和丢失功能至关重要，并影响结果的质量。在这项工作中，提出了一种修改了具有分层跳过连接的Reset架构，以恢复低剂量数字乳房X光检查。我们将恢复的图像与标准的全剂量图像进行比较。此外，我们评估了此任务的几个损失函数的性能。出于培训目的，我们从回顾性临床乳腺X线摄影考试的400次图像数据集中提取了256,000个图像贴片，其中模拟了不同的剂量水平以产生低和标准剂量对。为了在真实情况下验证网络，使用物理拟人乳房乳房映射来在商业上可获得的乳房X线摄影系统中获得真实的低剂量和标准全剂量图像，然后通过我们培训的模型处理。以前呈现的低剂量数字乳房X线摄影的分析恢复模型用作这项工作中的基准。通过信噪比（SNR）进行客观评估，并且平均归一化平方误差（MNSE），分解成残余噪声和偏置。结果表明，感知损失功能（PL4）能够实现全剂量采集的几乎相同的噪声水平，同时导致与其他损耗功能相比较小的信号偏差。

We describe a Physics-Informed Neural Network (PINN) that simulates the flow induced by the astronomical tide in a synthetic port channel, with dimensions based on the Santos - S\~ao Vicente - Bertioga Estuarine System. PINN models aim to combine the knowledge of physical systems and data-driven machine learning models. This is done by training a neural network to minimize the residuals of the governing equations in sample points. In this work, our flow is governed by the Navier-Stokes equations with some approximations. There are two main novelties in this paper. First, we design our model to assume that the flow is periodic in time, which is not feasible in conventional simulation methods. Second, we evaluate the benefit of resampling the function evaluation points during training, which has a near zero computational cost and has been verified to improve the final model, especially for small batch sizes. Finally, we discuss some limitations of the approximations used in the Navier-Stokes equations regarding the modeling of turbulence and how it interacts with PINNs.

Non-invasive prostate cancer detection from MRI has the potential to revolutionize patient care by providing early detection of clinically-significant disease (ISUP grade group >= 2), but has thus far shown limited positive predictive value. To address this, we present an MRI-based deep learning method for predicting clinically significant prostate cancer applicable to a patient population with subsequent ground truth biopsy results ranging from benign pathology to ISUP grade group~5. Specifically, we demonstrate that mixed supervision via diverse histopathological ground truth improves classification performance despite the cost of reduced concordance with image-based segmentation. That is, where prior approaches have utilized pathology results as ground truth derived from targeted biopsies and whole-mount prostatectomy to strongly supervise the localization of clinically significant cancer, our approach also utilizes weak supervision signals extracted from nontargeted systematic biopsies with regional localization to improve overall performance. Our key innovation is performing regression by distribution rather than simply by value, enabling use of additional pathology findings traditionally ignored by deep learning strategies. We evaluated our model on a dataset of 973 (testing n=160) multi-parametric prostate MRI exams collected at UCSF from 2015-2018 followed by MRI/ultrasound fusion (targeted) biopsy and systematic (nontargeted) biopsy of the prostate gland, demonstrating that deep networks trained with mixed supervision of histopathology can significantly exceed the performance of the Prostate Imaging-Reporting and Data System (PI-RADS) clinical standard for prostate MRI interpretation.

In this work, we demonstrate the offline FPGA realization of both recurrent and feedforward neural network (NN)-based equalizers for nonlinearity compensation in coherent optical transmission systems. First, we present a realization pipeline showing the conversion of the models from Python libraries to the FPGA chip synthesis and implementation. Then, we review the main alternatives for the hardware implementation of nonlinear activation functions. The main results are divided into three parts: a performance comparison, an analysis of how activation functions are implemented, and a report on the complexity of the hardware. The performance in Q-factor is presented for the cases of bidirectional long-short-term memory coupled with convolutional NN (biLSTM + CNN) equalizer, CNN equalizer, and standard 1-StpS digital back-propagation (DBP) for the simulation and experiment propagation of a single channel dual-polarization (SC-DP) 16QAM at 34 GBd along 17x70km of LEAF. The biLSTM+CNN equalizer provides a similar result to DBP and a 1.7 dB Q-factor gain compared with the chromatic dispersion compensation baseline in the experimental dataset. After that, we assess the Q-factor and the impact of hardware utilization when approximating the activation functions of NN using Taylor series, piecewise linear, and look-up table (LUT) approximations. We also show how to mitigate the approximation errors with extra training and provide some insights into possible gradient problems in the LUT approximation. Finally, to evaluate the complexity of hardware implementation to achieve 400G throughput, fixed-point NN-based equalizers with approximated activation functions are developed and implemented in an FPGA.

The application of combinatorial optimization problems to solving the problems of planning processes for industries based on a fund of reconfigurable production resources is considered. The results of their solution by mixed integer programming methods are presented.

Multi-agent artificial intelligence research promises a path to develop intelligent technologies that are more human-like and more human-compatible than those produced by "solipsistic" approaches, which do not consider interactions between agents. Melting Pot is a research tool developed to facilitate work on multi-agent artificial intelligence, and provides an evaluation protocol that measures generalization to novel social partners in a set of canonical test scenarios. Each scenario pairs a physical environment (a "substrate") with a reference set of co-players (a "background population"), to create a social situation with substantial interdependence between the individuals involved. For instance, some scenarios were inspired by institutional-economics-based accounts of natural resource management and public-good-provision dilemmas. Others were inspired by considerations from evolutionary biology, game theory, and artificial life. Melting Pot aims to cover a maximally diverse set of interdependencies and incentives. It includes the commonly-studied extreme cases of perfectly-competitive (zero-sum) motivations and perfectly-cooperative (shared-reward) motivations, but does not stop with them. As in real-life, a clear majority of scenarios in Melting Pot have mixed incentives. They are neither purely competitive nor purely cooperative and thus demand successful agents be able to navigate the resulting ambiguity. Here we describe Melting Pot 2.0, which revises and expands on Melting Pot. We also introduce support for scenarios with asymmetric roles, and explain how to integrate them into the evaluation protocol. This report also contains: (1) details of all substrates and scenarios; (2) a complete description of all baseline algorithms and results. Our intention is for it to serve as a reference for researchers using Melting Pot 2.0.